MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine

Asthma {40000140}

Record Keys


Definition:
Asthma
Class:[  ]

Details


Other Terms:[  ]
Authoring date:
2020-09-06

Links


Meta Information


ICD:[  ]
Category:
Pulmonary
MedDra ID:
10003553
MedDra Level:
4

Notes


[  ]

Shared Notes


  • [1.18
    - Severe respiratory viral infection with respiratory syncytial virus (RSV) and rhinovirus (RV) is associated with increased risk of developing asthma, and as such, these viruses are considered asthmagenic.
    - Mice nasally exposed to two distinct strains of the commensal bacterial species Lactobacillus rhamnosus (LR05 and LR06) were protected against subsequent RSV infection.
    - Protection was associated with increased levels of IFN-β, IFN-γ, IL-6, and TNF-α in both BAL and serum samples, which contributed to viral clearance.

Common References