MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine

Celiac disease {40000137}

Record Keys


Definition:
Celiac disease
Class:[  ]

Details


Other Terms:
Coeliac disease
Authoring date:
2020-09-06

Links


Meta Information


ICD:[  ]
Category:
Gastroenterologic
MedDra ID:[  ]
MedDra Level:[  ]

Notes


[  ]

Shared Notes


  • [1.1
    - An increased Bacteroides vulgatus prevalence was associated with the genotype of infants at high risk of celiac disease development. (1)
    - Bacteroides fragilis has been associated with an increased risk for celiac disease development in genetically predisposed infants who were formula-fed.
    - Polysaccharide A produced by Bacteroides fragilis direct the immune system via its ability to direct the development of CD4+ T cells, thus inducing the differentiation of Th1-lineage.
    - It seems likely that increased abundance of Bacteroides contributes to the Th1 response found in the small intestinal mucosa of celiac disease patients.

Common References