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- Among bacterial species with higher abundance in the psoriasis gut microbiome, Bacteroides vulgatus and Parasutterella excrementihominis have been associated with other immune-mediated diseases.
- Increased intestinal colonization of Bacteroides vulgatus and elevated Bacteroides vulgatus reactive serum antibodies have been reported in ulcerative colitis patients.
- Moreover, colonization of Bacteroides vulgatus is sufficient to promote colitis in several animal models, which further supports the active role of Bacteroides vulgatus in development of colitis.
- The abundance of Akkermansia muciniphila was significantly reduced in patients with psoriasis .
- A. muciniphila is believed to have an important function in the pathogenesis of IBD and obesity; therefore, A. muciniphila, which is an indicator of health status, may be a key node for psoriasis as well as IBD and obesity. (1)
- Altered gut barrier in psoriasis is associated with gastrointestinal symptoms, systemic inflammatory profile and the increased blood concentration of gut microbiota-derived metabolite – TMAO.
- Biologic therapy may have an impact on the composition of the gut microbiome of psoriatic patients.
- The psoriatic subject showed a decrease in Firmicutes abundance and an increase in Proteobacteria abundance.
- An increase in Streptococcaceae, Rhodobacteraceae, Campylobacteraceae and Moraxellaceae has been observed in psoriatic subject.
- [1.1] Psoriatic patients have a distinct structural and functional fecal microbiota compared with controls   [The Journal of Dermatology] [Journal]
- [1.2] Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization   [Microbiome] [Journal]
- [1.3] Dysbiosis of skin microbiota in psoriatic patients: co-occurence of fungal and bacterial communities   [Frontiers in Microbiology] [Journal]
- [1.4] Dysbiosis of gut microbiota was closely associated with psoriasis   [Science China Life Sciences] [Journal]
- [1.5] The Akkermansia muciniphila is a gut microbiota signature in psoriasis   [Experimental Dermatology] [Journal]
- [1.6] Gut microbiota dysbiosis in a cohort of patients with psoriasis   [British Journal of Dermatology] [Journal]
- [1.7] Microbiome-host interplay in atopic dermatitis and psoriasis   [Nature communications] [Journal]
- [1.8] Intestinal microbiota profiling and predicted metabolic dysregulation in psoriasis patients   [Experimental Dermatology] [Journal]
- [1.9] Gut microbial composition in patients with psoriasis   [Scientific Reports] [Journal]
- [1.10] Salivary microbiota and inflammation-related proteins in patients with psoriasis   [Oral Diseases] [Journal]
- [1.11] Community differentiation of the cutaneous microbiota in psoriasis   [Microbiome] [Journal]
- [1.12] Distribution of Malassezia species in patients with psoriasis and healthy individuals in Tehran, Iran   [Journal of Cutaneous Pathology] [Journal]
- [1.13] Molecular characterization of the skin fungal microbiome in patients with psoriasis   [Journal of Dermatology] [Journal]
- [1.14] Molecular analysis of fungal microbiota in samples from healthy human skin and psoriatic lesions   [Journal of Clinical Microbiology] [Journal]
- [1.15] Combined culture and metagenomic analyses reveal significant shifts in the composition of the cutaneous microbiome in psoriasis   [British Journal of Dermatology] [Journal]
- [1.16] Unexplored diversity and strain-level structure of the skin microbiome associated with psoriasis   [npj Biofilms and Microbiomes] [Journal]
- [1.17] Substantial alterations of the cutaneous bacterial biota in psoriatic lesions.   [PLOS ONE] [Journal]
- [1.18] Comparison of bacterial microbiota in skin biopsies from normal and psoriatic skin.   [Arch Dermatol Res] [Journal]
- [1.19] Decreased bacterial diversity characterizes an altered gut microbiota in psoriatic arthritis and resembles dysbiosis of inflammatory bowel disease.   [Arthritis Rheumatol] [Journal]
- [1.20] Clinical Implications of Intestinal Barrier Damage in Psoriasis  [Research]  [Dovepress] [Journal]
- [1.21] Gut microbiome profile in psoriatic patients treated and untreated with biologic therapy  [Abstract]  [The Journal of Dermatology] [Journal]
- [1.22] Skin microbiota of first cousins affected by psoriasis and atopic dermatitis  [Review]  [Clinical and Molecular allergy] [Journal]